Effectiveness of Hexetidine 0.1% Compared to Chlorhexidine Digluconate 0.12% in Eliminating Candida Albicans Colonizing Dentures: A Randomized Clinical In Vivo Study
Identifieur interne : 001194 ( Main/Exploration ); précédent : 001193; suivant : 001195Effectiveness of Hexetidine 0.1% Compared to Chlorhexidine Digluconate 0.12% in Eliminating Candida Albicans Colonizing Dentures: A Randomized Clinical In Vivo Study
Auteurs : Georges Aoun [Liban] ; Maria Saadeh [Liban] ; Antoine Berberi [Liban]Source :
- Journal of International Oral Health : JIOH [ 0976-7428 ] ; 2015.
Abstract
Denture hygiene is an important factor in the prevention and treatment of denture stomatitis (DS). This study aimed to evaluate the efficacy of two different mouthwashes (chlorhexidine digluconate 0.12% and hexetidine 0.1%) in eliminating
A total of 60 denture wearers (20 men, 40 women; age range 40-80 years) with clinical evidence of DS were randomly divided into 2 test groups and 1 control group. The dentures of each test group were treated by immersion in one of the two mouthwashes while those of the control group were immersed in distilled water. Swab samples from the palatal surfaces of the upper dentures were collected before and after of cleaner use and examined mycologically.
Reduction in the number of colony-forming units of
Hexetidine 0.1% solution tested for the first time as a product of disinfection of the acrylic dentures showed average results after immersion of 8 night hours for 4 days and was less effective than chlorhexidine digluconate 0.12%.
Url:
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588790
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516077
PubMed: 26464531
PubMed Central: 4588790
Affiliations:
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id="aff2">Chief of Clinical Services, Department of Orthodontics, School of Dentistry, Lebanese University, Beirut, Lebanon</nlm:aff><country xml:lang="fr">Liban</country><wicri:regionArea>Chief of Clinical Services, Department of Orthodontics, School of Dentistry, Lebanese University, Beirut</wicri:regionArea><wicri:noRegion>Beirut</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3">Clinical Associate, Department of Orthodontics and Dentofacial Orthopedics, American University of Beirut, Lebanon</nlm:aff><country xml:lang="fr">Liban</country><wicri:regionArea>Clinical Associate, Department of Orthodontics and Dentofacial Orthopedics, American University of Beirut</wicri:regionArea><wicri:noRegion>American University of Beirut</wicri:noRegion></affiliation></author><author><name sortKey="Berberi, Antoine" sort="Berberi, Antoine" uniqKey="Berberi A" first="Antoine" last="Berberi">Antoine Berberi</name><affiliation wicri:level="1"><nlm:aff id="aff4">Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Lebanese University, Beirut, Lebanon</nlm:aff><country xml:lang="fr">Liban</country><wicri:regionArea>Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Lebanese University, Beirut</wicri:regionArea><wicri:noRegion>Beirut</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26464531</idno><idno type="pmc">4588790</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588790</idno><idno type="RBID">PMC:4588790</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000340</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000340</idno><idno type="wicri:Area/Pmc/Curation">000340</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000340</idno><idno type="wicri:Area/Pmc/Checkpoint">000E42</idno><idno type="wicri:explorRef" 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xml:lang="fr">Liban</country><wicri:regionArea>Assistant Professor, Department of Oral Pathology and Diagnosis, School of Dentistry, Lebanese University, Beirut</wicri:regionArea><wicri:noRegion>Beirut</wicri:noRegion></affiliation></author><author><name sortKey="Saadeh, Maria" sort="Saadeh, Maria" uniqKey="Saadeh M" first="Maria" last="Saadeh">Maria Saadeh</name><affiliation wicri:level="1"><nlm:aff id="aff2">Chief of Clinical Services, Department of Orthodontics, School of Dentistry, Lebanese University, Beirut, Lebanon</nlm:aff><country xml:lang="fr">Liban</country><wicri:regionArea>Chief of Clinical Services, Department of Orthodontics, School of Dentistry, Lebanese University, Beirut</wicri:regionArea><wicri:noRegion>Beirut</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3">Clinical Associate, Department of Orthodontics and Dentofacial Orthopedics, American University of Beirut, Lebanon</nlm:aff><country xml:lang="fr">Liban</country><wicri:regionArea>Clinical Associate, Department of Orthodontics and Dentofacial Orthopedics, American University of Beirut</wicri:regionArea><wicri:noRegion>American University of Beirut</wicri:noRegion></affiliation></author><author><name sortKey="Berberi, Antoine" sort="Berberi, Antoine" uniqKey="Berberi A" first="Antoine" last="Berberi">Antoine Berberi</name><affiliation wicri:level="1"><nlm:aff id="aff4">Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Lebanese University, Beirut, Lebanon</nlm:aff><country xml:lang="fr">Liban</country><wicri:regionArea>Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Lebanese University, Beirut</wicri:regionArea><wicri:noRegion>Beirut</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of International Oral Health : JIOH</title><idno type="ISSN">0976-7428</idno><idno type="eISSN">0976-1799</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="st1"><title>Background:</title><p>Denture hygiene is an important factor in the prevention and treatment of denture stomatitis (DS). This study aimed to evaluate the efficacy of two different mouthwashes (chlorhexidine digluconate 0.12% and hexetidine 0.1%) in eliminating <italic>Candida albicans</italic> on dentures.</p></sec><sec id="st2"><title>Materials and Methods:</title><p>A total of 60 denture wearers (20 men, 40 women; age range 40-80 years) with clinical evidence of DS were randomly divided into 2 test groups and 1 control group. The dentures of each test group were treated by immersion in one of the two mouthwashes while those of the control group were immersed in distilled water. Swab samples from the palatal surfaces of the upper dentures were collected before and after of cleaner use and examined mycologically.</p></sec><sec id="st3"><title>Results:</title><p>Reduction in the number of colony-forming units of <italic>Candida albicans</italic> after immersion of the dentures with chlorhexidine digluconate 0.12% was significantly greater than that of the group using hexetidine 0.1% and those of the control group.</p></sec><sec id="st4"><title>Conclusion:</title><p>Hexetidine 0.1% solution tested for the first time as a product of disinfection of the acrylic dentures showed average results after immersion of 8 night hours for 4 days and was less effective than chlorhexidine digluconate 0.12%.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Budtz Jorgensen, E" uniqKey="Budtz Jorgensen E">E Budtz-Jörgensen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gendreau, L" 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M">M Sixou</name></author><author><name sortKey="Hamel, O" uniqKey="Hamel O">O Hamel</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Liban</li></country></list><tree><country name="Liban"><noRegion><name sortKey="Aoun, Georges" sort="Aoun, Georges" uniqKey="Aoun G" first="Georges" last="Aoun">Georges Aoun</name></noRegion><name sortKey="Berberi, Antoine" sort="Berberi, Antoine" uniqKey="Berberi A" first="Antoine" last="Berberi">Antoine Berberi</name><name sortKey="Saadeh, Maria" sort="Saadeh, Maria" uniqKey="Saadeh M" first="Maria" last="Saadeh">Maria Saadeh</name><name sortKey="Saadeh, Maria" sort="Saadeh, Maria" uniqKey="Saadeh M" first="Maria" last="Saadeh">Maria Saadeh</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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